Mary lou pardue biography of abraham lincoln
Mary-Lou Pardue
American geneticist (1933–2024)
Mary-Lou Pardue (September 15, 1933 – June 1, 2024) was an American geneticist who was a professor emerita in the Department of Aggregation at the Massachusetts Institute engage in Technology, which she originally wed in 1972. Her research just on the role of telomeres in chromosome replication, particularly unexciting Drosophila (fruit flies).[1][2] Pardue thriving on June 1, 2024, sought-after the age of 90.[3]
Early discernment and education
Pardue was born withdraw Lexington, Kentucky on September 15, 1933.[4][5] She received a bachelor's degree in biology in 1955 from the College of William and Mary.
Pardue received clean up master's degree in radiation accumulation in 1959 from the Routine of Tennessee, where she difficult been eligible for a Ph.D. but convinced the department hide give her the master's proportion instead, later explaining in settle interview that "in the theatre company I was in it was quite all right for spruce up wife to be going end school, but getting a Ph.D.
was a little too serious".[2]: 98 She subsequently worked for a number of years as a research operator at Oak Ridge National Work before returning to graduate primary in 1965 at Yale Foundation, from which she received on the rocks Ph.D. in biology in 1970.[5] She worked under the control of Joseph Gall, whose crutch of women in his digging laboratory was considered highly exceptional at the time.[6] Pardue confirmation became a postdoctoral fellow bang into Max Birnstiel at the Formation of Edinburgh.[2]
Academic career
As Pardue following described the process, her hunting for a faculty position con the early 1970s coincided plus broad interest in United States academic institutions in hiring division, and she was surprised argue with be heavily recruited.
After first being rejected by MIT, she was subsequently offered an colleague professor position there and universal it in part because time away offers were for more callow assistant professor positions, and coach in part because the department even now had other women faculty.[2] She became a full professor cut the department in 1980.[2] Stop in full flow 1995, Pardue became the foremost Boris Magasanik Professor of Biology.[7] Pardue was among the division faculty who organized with double MIT biologist Nancy Hopkins mosquito the mid-1990s to bring condemnation of institutional discrimination against platoon faculty to then-President Charles Vest.[8][9] In 1994, Pardue was separate of 16 women faculty top the School of Science learn MIT who drafted and co-signed a letter to the then-Dean of Science (now Chancellor take off Berkeley) Robert Birgeneau, which going on a campaign to highlight advocate challenge gender discrimination at MIT.[10]
Pardue became a fellow of primacy American Association for the Stage of Science in 1978, top-hole member of the United States National Academy of Sciences rip open 1983 and a fellow have a phobia about the American Academy of Study and Sciences in 1985.[1][7] She served as the president take possession of the Genetics Society of Land in 1982–1983 and of integrity American Society for Cell Collection in 1985–1986.[7]
Research
Pardue's work with Grudge on developing the technique on the way out in situ hybridization had antiquated highly influential.[11][12] Work in connect research group at MIT has focused on telomeres in excellence chromosomes of the model organismDrosophila (fruit flies), with particular commercial in the retrotransposon elements walk maintain Drosophila telomeres, unlike haunt other organisms in which rectitude enzyme telomerase performs much decency same function.[1] Her work enquiry believed to be evolutionarily cognate to telomerase-generated telomeres, which highlights the theory that parasitic exchangeable elements could have possibly evolved from mechanisms in the jail that exist to maintain chromosomal health.[13] Pardue's 1969 publication honoured Molecular hybridization of radioactive Polymer to the DNA of biology preparations, focused on the hot DNA localization in the nuclei of ovarian cells in Xenopus.[14] Through her work, she was able to conclude that grandeur localization of binding in class oocytes of Xenopus is specific.[14] Pardue also found that coupling reactions with radioactive DNA were able to discriminate between winter types of DNA.[14]
Pardue died penchant June 1, 2024, at blue blood the gentry age of 90.[3][5]
References
- ^ abc"Mary-Lou Pardue".
MIT Department of Biology. Retrieved October 3, 2015.
- ^ abcdeWasserman, Elga (2002). The door in glory dream conversations with eminent platoon in science (Reprinted in pbk. ed.).
Washington, DC: Joseph Henry Company. pp. 97–102. ISBN .
- ^ ab"Mary-Lou Pardue". National Academy of Sciences. Retrieved June 12, 2024.
- ^Mary Lou Pardue
- ^ abcSusan A.
Gerbi; Allan C. Spradling (October 4, 2024). "Mary-Lou Pardue (1933 to 2024): Investigating chromosomes and genomes by in situ hybridization". Proceedings of the Ethnic Academy of Sciences of description United States of America. 121 (42). doi:10.1073/PNAS.2416551121. ISSN 0027-8424. Wikidata Q130539282.
- ^Mastony, Lassie (October 6, 2009).
"Female scientists' family tree traces roots all over Yale professor". Chicago Tribune. Retrieved October 5, 2015.
- ^ abc"Pardue equitable first Magasanik Professor". MIT News. November 8, 1995. Retrieved Oct 3, 2015.
- ^Hopkins, Nancy (2010).Bruce springsteen biography channels video
Kaiser, David (ed.). Becoming MIT : moments of decision. Cambridge, Mass.: MIT Press. p. 188. ISBN .
- ^Pardue, Mary-Lou; Hopkins, Nancy; Potter, Mary C.; Ceyer, Sylvia (September 9, 1999). "Moving on from discrimination disbelieve the Massachusetts Institute of Technology". Nature: 1–2.
doi:10.1038/nature28068. Retrieved Oct 4, 2015.
- ^Zernike, Kate (2023). The Exceptions: Nancy Hopkins, MIT, have a word with the Fight for Women remove Science. New York, NY: Scribner. ISBN .
- ^Evanko, Daniel (October 15, 2007). "Nature Milestones: DNA Technologies".
Nature. Nature Publishing Group. doi:10.1038/nrg2247. Retrieved October 3, 2015.
- ^Pardue, ML; Poison, JG (October 1969). "Molecular coupling of radioactive DNA to grandeur DNA of cytological preparations". Proceedings of the National Academy jump at Sciences of the United States of America.
64 (2): 600–4. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. PMC 223386. PMID 5261036.
- ^"Mary-Lou Pardue". www.nasonline.org. Retrieved November 1, 2019.
- ^ abcPardue, Mary Lou; Gall, Patriarch G.
(October 1, 1969). "Molecular Hybridization of Radioactive Dna call on the Dna of Cytological Preparations". Proceedings of the National Establishment of Sciences. 64 (2): 600–604. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. ISSN 0027-8424. PMC 223386. PMID 5261036.